Single Intraocular Pressure Measurements and Diurnal Intraocular Pressure Profiles

Overview

Journal Am J Ophthalmol

Specialty Ophthalmology

Date 2005 Jun 15

PMID 15953461

Citations 18

Authors

Jost B Jonas

Wido Budde

Andrea Stroux

Isabel M Oberacher-Velten

Anselm Junemann

Affiliations

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Abstract

Purpose: To evaluate the probability of a single intraocular pressure measurement to be the highest measurement within a diurnal intraocular pressure profile.

Design: Hospital-based clinical, observational study.

Methods: The study included 3,025 day-and-night intraocular pressure profiles measured on 1,072 eyes of 547 Caucasian glaucoma patients or glaucoma suspects. Applanation tonometry was performed at 7 am, noon, 5 pm, 9 pm, and midnight.

Results: Intraocular pressure measurements were highest at 7 am, noon, 5 pm, 9 pm, and midnight, respectively, in 20.4%, 17.8%, 21.3% 13.9%, and 26.7% of the profiles, respectively. The measurement taken at 7 am was significantly (P < .001) closest to the maximal value of the profile.

Conclusions: Any single intraocular pressure measurement taken between 7 am and 9 pm has a higher than 75% chance to miss the highest point of a diurnal curve. Intraocular pressure may be measured at different times of the day to have the best chance of observing the maximal value.

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