Residues in the Murine Leukemia Virus Capsid That Differentially Govern Resistance to Mouse Fv1 and Human Ref1 Restrictions

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2005 Apr 29

PMID 15858043

Citations 21

Authors

Adeline Lassaux

Marc Sitbon

Jean-Luc Battini

Affiliations

Soon will be listed here.

Abstract

We identified new residues within a 101-amino-acid stretch of the murine leukemia virus capsid that differentially modulate resistance and susceptibility to the mouse Fv1 and human Ref1 genes. Among these residues, aspartate 92 and histidine 117 are both required for Fv1(b) resistance, whereas the latter is sufficient to confer Ref1 resistance.

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