Single Vaginal Ectopic Ureter of Fetal Metanephric Duct Origin, Ipsilateral Kidney Agenesis, and Ipsilateral Rudimentary Uterine Horn of the Bicornuate Uterus

Background: Congenital anomalies arising from the urogenital tracts are common. We experienced two cases of specific urogenital anomalies.

Case: Two Japanese women had a single ectopic ureter opening in the central wall of the vagina, ipsilateral kidney agenesis, and ipsilateral rudimentary uterine horn of the bicornuate uterus. One had squamous cell carcinoma of the uterine cervix, and the other had adenocarcinoma of the vagina arising from the ectopic ureter meatus, which was histologically confirmed as fetal metanephric duct remnant. One had vesico-vaginal fistula postoperatively, resulting from separating the ureter-like duct from the bladder.

Conclusion: Concomitant occurrence of anomalies suggests the common genetic backgrounds, which are not well known. Clinically, the ectopic vaginal ureter is important as a possible background of vaginal adenocarcinoma, and information on the ureter-like duct course is required during surgery.