Deubiquitination, a New Function of the Severe Acute Respiratory Syndrome Coronavirus Papain-like Protease?

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2005 Mar 16

PMID 15767458

Citations 69

Authors

Traian Sulea

Holger A Lindner

Enrico O Purisima

Robert Menard

Affiliations

Soon will be listed here.

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References

Sri Krishna S, Grishin N . The finger domain of the human deubiquitinating enzyme HAUSP is a zinc ribbon. Cell Cycle. 2004; 3(8):1046-9. View

Thiel V, Ivanov K, Putics A, Hertzig T, Schelle B, Bayer S . Mechanisms and enzymes involved in SARS coronavirus genome expression. J Gen Virol. 2003; 84(Pt 9):2305-2315. DOI: 10.1099/vir.0.19424-0. View

Hughes S, Bonilla P, Weiss S . Identification of the murine coronavirus p28 cleavage site. J Virol. 1995; 69(2):809-13. PMC: 188646. DOI: 10.1128/JVI.69.2.809-813.1995. View

Bonilla P, Hughes S, Weiss S . Characterization of a second cleavage site and demonstration of activity in trans by the papain-like proteinase of the murine coronavirus mouse hepatitis virus strain A59. J Virol. 1997; 71(2):900-9. PMC: 191137. DOI: 10.1128/JVI.71.2.900-909.1997. View

Teng H, Pinon J, Weiss S . Expression of murine coronavirus recombinant papain-like proteinase: efficient cleavage is dependent on the lengths of both the substrate and the proteinase polypeptides. J Virol. 1999; 73(4):2658-66. PMC: 104021. DOI: 10.1128/JVI.73.4.2658-2666.1999. View

Herold J, Siddell S, Gorbalenya A . A human RNA viral cysteine proteinase that depends upon a unique Zn2+-binding finger connecting the two domains of a papain-like fold . J Biol Chem. 1999; 274(21):14918-25. PMC: 8005983. DOI: 10.1074/jbc.274.21.14918. View

Harcourt B, Jukneliene D, Kanjanahaluethai A, Bechill J, Severson K, Smith C . Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity. J Virol. 2004; 78(24):13600-12. PMC: 533933. DOI: 10.1128/JVI.78.24.13600-13612.2004. View

Ritchie K, Hahn C, Kim K, Yan M, Rosario D, Li L . Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection. Nat Med. 2004; 10(12):1374-8. DOI: 10.1038/nm1133. View

Ziebuhr J, Thiel V, Gorbalenya A . The autocatalytic release of a putative RNA virus transcription factor from its polyprotein precursor involves two paralogous papain-like proteases that cleave the same peptide bond. J Biol Chem. 2001; 276(35):33220-32. PMC: 8009867. DOI: 10.1074/jbc.M104097200. View

10.

Kim J, Spence R, Currier P, Lu X, Denison M . Coronavirus protein processing and RNA synthesis is inhibited by the cysteine proteinase inhibitor E64d. Virology. 1995; 208(1):1-8. PMC: 7131484. DOI: 10.1006/viro.1995.1123. View

11.

Hu M, Li P, Li M, Li W, Yao T, Wu J . Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde. Cell. 2003; 111(7):1041-54. DOI: 10.1016/s0092-8674(02)01199-6. View

12.

Snijder E, Bredenbeek P, Dobbe J, Thiel V, Ziebuhr J, Poon L . Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J Mol Biol. 2003; 331(5):991-1004. PMC: 7159028. DOI: 10.1016/s0022-2836(03)00865-9. View

13.

Balakirev M, Jaquinod M, Haas A, Chroboczek J . Deubiquitinating function of adenovirus proteinase. J Virol. 2002; 76(12):6323-31. PMC: 136223. DOI: 10.1128/jvi.76.12.6323-6331.2002. View

14.

Gosert R, Kanjanahaluethai A, Egger D, Bienz K, Baker S . RNA replication of mouse hepatitis virus takes place at double-membrane vesicles. J Virol. 2002; 76(8):3697-708. PMC: 136101. DOI: 10.1128/jvi.76.8.3697-3708.2002. View

15.

Ginalski K, Elofsson A, Fischer D, Rychlewski L . 3D-Jury: a simple approach to improve protein structure predictions. Bioinformatics. 2003; 19(8):1015-8. DOI: 10.1093/bioinformatics/btg124. View

16.

Kanjanahaluethai A, Jukneliene D, Baker S . Identification of the murine coronavirus MP1 cleavage site recognized by papain-like proteinase 2. J Virol. 2003; 77(13):7376-82. PMC: 164800. DOI: 10.1128/jvi.77.13.7376-7382.2003. View

17.

Dong S, Baker S . Determinants of the p28 cleavage site recognized by the first papain-like cysteine proteinase of murine coronavirus. Virology. 1994; 204(2):541-9. PMC: 7130860. DOI: 10.1006/viro.1994.1567. View