The Use of Patch Testing in the Diagnosis of Food Allergy
Overview
Pulmonary Medicine
Affiliations
Diagnosing food allergies can be challenging to the practitioner. Our armamentarium includes standardized skin prick testing, radioallergoimmunosorbent (RAST) testing, and food challenges. These methods have certainly been helpful in the IgE-mediated disorders, including urticaria and anaphylaxis. However, diagnosing patients who have the non-IgE (cell-mediated) or mixed (IgE and cell-mediated) disorders remains challenging with our current diagnostic methods. Recent studies have examined the use of patch testing for these food-allergic patients, specifically those with atopic dermatitis and eosinophilic esophagitis. In this article, we review literature regarding patch testing: its methods, its statistical usefulness, and its potential future role.
Eosinophilic esophagitis phenotypes: Ready for prime time?.
Atkins D, Furuta G, Liacouras C, Spergel J Pediatr Allergy Immunol. 2017; 28(4):312-319.
PMID: 28339136 PMC: 5479411. DOI: 10.1111/pai.12715.
An allergist's perspective to the evaluation of Eosinophilic Esophagitis.
Spergel J Best Pract Res Clin Gastroenterol. 2015; 29(5):771-781.
PMID: 26552776 PMC: 4641822. DOI: 10.1016/j.bpg.2015.06.011.
Eosinophilic Esophagitis: A Comprehensive Review.
Cianferoni A, Spergel J Clin Rev Allergy Immunol. 2015; 50(2):159-74.
PMID: 26194940 DOI: 10.1007/s12016-015-8501-z.
International survey on evaluation and management of eosinophilic esophagitis.
Shaffer C, Ghaffari G World Allergy Organ J. 2013; 5(9):95-102.
PMID: 23283208 PMC: 3694720. DOI: 10.1097/WOX.0b013e3182690759.
Lucarelli S, Di Nardo G, Lastrucci G, DAlfonso Y, Marcheggiano A, Federici T BMC Gastroenterol. 2011; 11:82.
PMID: 21762530 PMC: 3224143. DOI: 10.1186/1471-230X-11-82.