» Articles » PMID: 23283208

International Survey on Evaluation and Management of Eosinophilic Esophagitis

Overview
Date 2013 Jan 4
PMID 23283208
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Background: : Recommendations regarding evaluation and management of eosinophilic esophagitis (EoE) remain incompletely defined. This survey assesses: how providers across the world diagnose, evaluate, and treat EoE and how educational activities affect management.

Methods: : A web-based survey was sent to the members of World Allergy Organization, American College of Allergy, Asthma, and Immunology, and American Academy of Allergy, Asthma, and Immunology. A χ analysis compared responses based on personal and practice demographics and participation in educational activities.

Results: : Of the 200 respondents, 68.5% were from the United States. The majority were allergists, who require biopsy to diagnose EoE, perform allergy testing, and obtain follow-up biopsy after treatment. The following variables had significant differences: (1) US practitioners were more likely to test for immediate-type hypersensitivity to foods and obtain follow-up endoscopic biopsies after the initial treatment; (2) Practitioners encountering patients with EoE more frequently were more likely to ask about personal and family history of atopy, test for immediate-type hypersensitivity to aeroallergens and foods, and recommend follow-up biopsy after treatment; and (3) Practitioners who participate more often in EoE workshops were more likely to perform patch testing for foods, while attendance at EoE lectures increased EoE management confidence.

Conclusions: : Diagnostic and management strategies differ based on practice location, EoE patient load, and participation in educational activities. Practitioners who attend more EoE lectures are more confident managing EoE.

Citing Articles

Assessing eosinophilic cationic protein as a biomarker for monitoring patients with eosinophilic esophagitis treated with specific exclusion diets.

Domenech Witek J, Jover Cerda V, Gil Guillen V, Domenech Clar J, Rodriguez Pacheco R World Allergy Organ J. 2017; 10(1):12.

PMID: 28360963 PMC: 5363006. DOI: 10.1186/s40413-017-0143-6.

References
1.
Mishra A, Schlotman J, Wang M, Rothenberg M . Critical role for adaptive T cell immunity in experimental eosinophilic esophagitis in mice. J Leukoc Biol. 2006; 81(4):916-24. DOI: 10.1189/jlb.1106653. View

2.
Mishra A, Hogan S, Brandt E, Rothenberg M . An etiological role for aeroallergens and eosinophils in experimental esophagitis. J Clin Invest. 2001; 107(1):83-90. PMC: 198543. DOI: 10.1172/JCI10224. View

3.
Kelly K, Lazenby A, Rowe P, Yardley J, Perman J, Sampson H . Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula. Gastroenterology. 1995; 109(5):1503-12. DOI: 10.1016/0016-5085(95)90637-1. View

4.
Penfield J, Lang D, Goldblum J, Lopez R, Falk G . The role of allergy evaluation in adults with eosinophilic esophagitis. J Clin Gastroenterol. 2009; 44(1):22-7. DOI: 10.1097/MCG.0b013e3181a1bee5. View

5.
Kagalwalla A, Sentongo T, Ritz S, Hess T, Nelson S, Emerick K . Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2006; 4(9):1097-102. DOI: 10.1016/j.cgh.2006.05.026. View