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Replicating Vesicles As Models of Primitive Cell Growth and Division

Overview
Publisher Elsevier
Specialty Biochemistry
Date 2004 Nov 24
PMID 15556412
Citations 49
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Abstract

Primitive cells, lacking the complex bio-machinery present in modern cells, would have had to rely on the self-organizing properties of their components and on interactions with their environment to achieve basic cellular functions such as growth and division. Many bilayer-membrane vesicles, depending on their composition and environment, can exhibit complex morphological changes such as growth, fusion, fission, budding, internal vesicle assembly and vesicle-surface interactions. The rich dynamic properties of these vesicles provide interesting models of how primitive cellular replication might have occurred in response to purely physical and chemical forces.

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