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Indirect Trapping of the Retroconjugate Addition Reaction Intermediate Involved in the Epimerization of Lobeline: Application to the Synthesis of (-)-sedamine

Overview
Journal J Org Chem
Publisher American Chemical Society
Specialty Chemistry
Date 2004 Nov 20
PMID 15549833
Citations 8
Authors
Guangrong Zheng
Linda P Dwoskin
Peter A Crooks
Affiliations
Soon will be listed here.
Abstract

Alkyl chloroformates induced indirect trapping of the retroconjugate addition reaction intermediate involved in the epimerization of lobeline is described. This strategy was applied to the conversion of (-)-lobeline to (-)-sedamine in high overall yield.

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References
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