Treatment of Advanced Non-small-cell Lung Cancer in Special Populations

Overview

Journal Oncology (Williston Park)

Specialty Oncology

Date 2004 Nov 6

PMID 15526837

Citations 8

Authors

Rogerio C Lilenbaum

Affiliations

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Abstract

The benefits of chemotherapy in non-small-cell lung cancer (NSCLC) patients remains, to some extent, restricted to younger patients with a good performance status (PS). It has long been assumed that chemotherapy is too toxic and of marginal benefit for elderly NSCLC patients and those with a PS of 2. Nevertheless, retrospective analyses and more recent prospective trials have suggested that such patients enjoy longer survival and a better quality of life when treated with chemotherapy. This article will review the data and discuss their clinical implications.

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