Plasmid-mediated Carbapenem-hydrolyzing Enzyme KPC-2 in an Enterobacter Sp

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2004 Oct 27

PMID 15504876

Citations 48

Authors

Ashfaque Hossain

M J Ferraro

R M Pino

R B Dew 3rd

E S Moland

T J Lockhart

K S Thomson

R V Goering

N D Hanson

Affiliations

Soon will be listed here.

Abstract

A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 beta-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 beta-lactamase by an Enterobacter sp.

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