Endothelial Cell Culture: Beginnings of Modern Vascular Biology

Overview

Journal J Clin Invest

Specialty General Medicine

Date 2004 Oct 19

PMID 15489946

Citations 24

Authors

Ralph L Nachman

Eric A Jaffe

Affiliations

Soon will be listed here.

Abstract

Endothelial cells derived from human umbilical veins were first successfully cultured in vitro in 1973. Weibel-Palade bodies and the von Willebrand factor antigen were used as morphological, immunohistochemical, and functional markers to unequivocally identify the cells. These landmark studies helped initiate the growth of modern vascular biology.

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