» Articles » PMID: 15463957

Established Cell Lines Used in Cystic Fibrosis Research

Overview
Journal J Cyst Fibros
Publisher Elsevier
Specialty Pulmonary Medicine
Date 2004 Oct 7
PMID 15463957
Citations 72
Authors
Affiliations
Soon will be listed here.
Abstract

The development of immortalized cell lines has been a significant benefit to the study of human disease, due to limitations in using primary cells and the availability of tissue. The immortalization of cells from cystic fibrosis (CF) patients as well as cells from non-CF individuals from tissues relevant to CF has been critical to enhancing our understanding of the physiological, biochemical and genetic mechanisms underlying CF and for the development of therapeutic strategies designed to manage CF pathology. A comprehensive list of immortalized cells from various tissue and species, with an emphasis on epithelial cells, is presented and discussed here.

Citing Articles

Differentiation of CD166-positive hPSC-derived lung progenitors into airway epithelial cells.

Goh K, Lu H, Tan E, Lee Z, Wong A, Tran T Biol Open. 2024; 13(10).

PMID: 39387302 PMC: 11554259. DOI: 10.1242/bio.061729.


Ligand-free biodegradable poly(beta-amino ester) nanoparticles for targeted systemic delivery of mRNA to the lungs.

Kavanagh E, Tzeng S, Sharma N, Cutting G, Green J Biomaterials. 2024; 313:122753.

PMID: 39217793 PMC: 11571037. DOI: 10.1016/j.biomaterials.2024.122753.


TNFRSF1B Signaling Blockade Protects Airway Epithelial Cells from Oxidative Stress.

Checa J, Fiol P, Guevara M, Aran J Antioxidants (Basel). 2024; 13(3).

PMID: 38539900 PMC: 10968085. DOI: 10.3390/antiox13030368.


Hypoxia-induced cystic fibrosis transmembrane conductance regulator dysfunction is a universal mechanism underlying reduced mucociliary transport in sinusitis.

Cho D, Zhang S, Norwood T, Skinner D, Hollis T, Ehrhardt M Int Forum Allergy Rhinol. 2023; 14(6):1058-1069.

PMID: 38073611 PMC: 11849962. DOI: 10.1002/alr.23309.


Multiomic Investigations into Lung Health and Disease.

Blutt S, Coarfa C, Neu J, Pammi M Microorganisms. 2023; 11(8).

PMID: 37630676 PMC: 10459661. DOI: 10.3390/microorganisms11082116.