Evaluation of Fluorinated Polymers As Coronary Stent Coating

Overview

Journal J Mater Sci Mater Med

Publisher Springer

Specialty Biomedical Engineering

Date 2004 Sep 7

PMID 15348033

Citations 2

Authors

I Verweire

E Schacht

B P Qiang

K Wang

I De Scheerder

Affiliations

Soon will be listed here.

Abstract

In this report, some fluorinated polyphosphazenes and polymethacrylates were selected for evaluation as coronary stent coating. After applying the polymer film by dipcoating, the stents were implanted in porcine coronary arteries. No acute thrombotic occlusions were observed. The neointimal proliferation was studied by a 6 week follow-up of the minimal lumen stented diameter, using quantitative coronary analysis. All polymers demonstrated a slight hyperplasia, resulting in a 10-20% lumen narrowing at follow-up. Only for one fluorinated polymethacrylate, PFM-P75, a minimal neointimal response (3% lumen narrowing) was found.

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