National Surveillance of Methicillin-resistant Staphylococcus Aureus in Belgian Hospitals Indicates Rapid Diversification of Epidemic Clones

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2004 Aug 26

PMID 15328144

Citations 24

Authors

Olivier Denis

Ariane Deplano

Claire Nonhoff

Raf De Ryck

Ricardo De Mendonca

Sylvianne Rottiers

Raymond Vanhoof

Marc J Struelens

Affiliations

Soon will be listed here.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains (n = 455) collected in 2001 from 100 Belgian hospitals were characterized by molecular typing and by resistance gene distribution to macrolides-lincosamides-streptogramins and to aminoglycoside antibiotics. Rapid diversification of MRSA clones, compared with results of previous surveys, was evidenced by the broad geographic distribution of seven major clones belonging to the pandemic MRSA clonal complexes 5, 8, 22, 30, and 45 by multilocus sequence typing.

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