After 'completion': the Changing Face of Human Chromosomes 21 and 22
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
In the four years since the publication of the first two 'complete' human chromosome sequences the type of research being done on each has shifted subtly, reflecting the impact of genomic data on biological science in general. There is now considerably more gene-expression evidence to support predicted genes, and the annotation of functions for previously unknown genes, including those implicated in disease, is gradually improving.
References
1.
Dunham I, Shimizu N, Roe B, Chissoe S, HUNT A, Collins J
. The DNA sequence of human chromosome 22. Nature. 1999; 402(6761):489-95.
DOI: 10.1038/990031.
View
2.
Hattori M, Fujiyama A, Taylor T, Watanabe H, Yada T, Park H
. The DNA sequence of human chromosome 21. Nature. 2000; 405(6784):311-9.
DOI: 10.1038/35012518.
View
3.
Venter J, Adams M, Myers E, Li P, Mural R, Sutton G
. The sequence of the human genome. Science. 2001; 291(5507):1304-51.
DOI: 10.1126/science.1058040.
View
4.
Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J
. Initial sequencing and analysis of the human genome. Nature. 2001; 409(6822):860-921.
DOI: 10.1038/35057062.
View
5.
Watanabe H, Fujiyama A, Hattori M, Taylor T, Toyoda A, Kuroki Y
. DNA sequence and comparative analysis of chimpanzee chromosome 22. Nature. 2004; 429(6990):382-8.
DOI: 10.1038/nature02564.
View