Analysing the Platelet Transcriptome

Overview

Journal Vox Sang

Specialty Hematology

Date 2004 Jun 24

PMID 15209877

Citations 6

Authors

I C Macaulay

P Carr

R Farrugia

N A Watkins

Affiliations

Soon will be listed here.

Abstract

Historical studies, using Northern blot hybridization, RT-PCR and cDNA library construction have demonstrated the presence of a variety of mRNA molecules in platelets. The development of microarray technology has allowed further characterization of the transcripts represented in the platelet transcriptome. In this review, these studies will be summarized and their findings in relation to the study of platelet function and the identification of disease risk genes discussed.

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Platelets Purification Is a Crucial Step for Transcriptomic Analysis.

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Platelets and platelet-like particles mediate intercellular RNA transfer.

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Protein synthesis by platelets: historical and new perspectives.

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