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ELVIRA HSV, a Yield Reduction Assay for Rapid Herpes Simplex Virus Susceptibility Testing

Overview
Journal Antimicrob Agents Chemother
Publisher American Society for Microbiology
Specialty Pharmacology
Date 2004 May 25
PMID 15155247
Citations 5
Authors
Ruzena Stranska
Rob Schuurman
David R Scholl
Joseph A Jollick
Carl J Shaw
Caroline Loef
Merjo Polman
Anton M van Loon
Affiliations
Soon will be listed here.
Abstract

A colorimetric yield reduction assay, ELVIRA (enzyme-linked virus inhibitor reporter assay) HSV, was developed to determine the antiviral drug susceptibilities of herpes simplex virus (HSV). It uses an HSV-inducible reporter cell line. This simple and rapid assay has an objective readout, low inoculum size, and good reproducibility. The results correlate well with those of the plaque reduction assay.

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