Natural Product Glycorandomization

Overview

Journal Bioorg Med Chem

Specialties Biochemistry
Chemistry

Date 2004 Apr 29

PMID 15112655

Citations 13

Authors

Jie Yang

Dirk Hoffmeister

Lesley Liu

Xun Fu

Jon S Thorson

Affiliations

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Abstract

glycorandomization is a chemoenzymatic strategy that overcomes the limitations in natural product derivatization associated with both solely chemistry-based approaches or in vivo engineering. In this article we present the basic strategies for glycorandomization development as a next-generation tool in drug discovery.

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