Occupational Exposure to Air Pollution and Cancer Risk Among Danish Urban Mail Carriers

Overview

Journal Int Arch Occup Environ Health

Specialty Environmental Health

Date 2004 Apr 27

PMID 15108001

Citations 14

Authors

Helle Soll-Johanning

Elsa Bach

Affiliations

Soon will be listed here.

Abstract

Objectives: Our objective was to study the risk of cancer associated with exposure to air pollution among mail carriers.

Methods: We carried out a retrospective cohort study of 17,233 persons who had been mail carriers during the period 1898-1996. Data on employment was obtained from company files. Data on cancer was obtained from the Danish Cancer Registry.

Results: Male mail carriers employed for more than 3 months had a low incidence of cancer, standardised incidence ratio (SIR) 0.92. For cancers related to air pollution the risk estimates were 0.96 for lung cancer, 0.91 for laryngeal cancer and 0.98 for bladder cancer. A significant low risk for cancer of the oesophagus (SIR 0.50), kidney (SIR 0.73), prostate (SIR 0.81) and skin (melanoma) (SIR 0.87) was seen. Among female mail carriers the risk pattern showed a significant excess of cancer of the cervix uteri (SIR 2.24).

Conclusion: In our study of mail carriers who had spent most of their day doing physical hard work outside in the general air pollution we saw no excess in cancers related to air pollution compared with the general population of Copenhagen. This might be due to the protective effect of physical activity.

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References

Hansen A, Christensen J, Sherson D . Estimation of reference values for urinary 1-hydroxypyrene and alpha-naphthol in Danish workers. Sci Total Environ. 1995; 163(1-3):211-9. DOI: 10.1016/0048-9697(95)04485-j. View

Hannerz H, Tuchsen F . Hospital admissions among male drivers in Denmark. Occup Environ Med. 2001; 58(4):253-60. PMC: 1740115. DOI: 10.1136/oem.58.4.253. View

Kjaer S, van den Brule A, Bock J, Poll P, Engholm G, Sherman M . Human papillomavirus--the most significant risk determinant of cervical intraepithelial neoplasia. Int J Cancer. 1996; 65(5):601-6. DOI: 10.1002/(SICI)1097-0215(19960301)65:5<601::AID-IJC8>3.0.CO;2-6. View

Zheng T, Cantor K, Zhang Y, Keim S, Lynch C . Occupational risk factors for brain cancer: a population-based case-control study in Iowa. J Occup Environ Med. 2001; 43(4):317-24. DOI: 10.1097/00043764-200104000-00005. View

Nielsen P, Andreassen A, Farmer P, Ovrebo S, Autrup H . Biomonitoring of diesel exhaust-exposed workers. DNA and hemoglobin adducts and urinary 1-hydroxypyrene as markers of exposure. Toxicol Lett. 1996; 86(1):27-37. DOI: 10.1016/0378-4274(96)83963-4. View

Nyberg F, Gustavsson P, Jarup L, Bellander T, Berglind N, Jakobsson R . Urban air pollution and lung cancer in Stockholm. Epidemiology. 2000; 11(5):487-95. DOI: 10.1097/00001648-200009000-00002. View

Hemminki K, Pershagen G . Cancer risk of air pollution: epidemiological evidence. Environ Health Perspect. 1994; 102 Suppl 4:187-92. PMC: 1566938. DOI: 10.1289/ehp.94102s4187. View

Zuskin E, Mustajbegovic J, Schachter E, Kern J, Vadjic V, Strok N . Respiratory findings in mail carriers. Int Arch Occup Environ Health. 2000; 73(2):136-43. DOI: 10.1007/s004200050019. View

Gamble J, Jones W, Minshall S . Epidemiological-environmental study of diesel bus garage workers: chronic effects of diesel exhaust on the respiratory system. Environ Res. 1987; 44(1):6-17. DOI: 10.1016/s0013-9351(87)80082-8. View

10.

Ulfvarson U, Alexandersson R . Reduction in adverse effect on pulmonary function after exposure to filtered diesel exhaust. Am J Ind Med. 1990; 17(3):341-7. DOI: 10.1002/ajim.4700170306. View

11.

Schouten L, Meijer H, Huveneers J, Kiemeney L . Urban-rural differences in cancer incidence in The Netherlands 1989-1991. Int J Epidemiol. 1996; 25(4):729-36. DOI: 10.1093/ije/25.4.729. View

12.

Kjaer S, Dahl C, Engholm G, Bock J, Lynge E, JENSEN O . Case-control study of risk factors for cervical neoplasia in Denmark. II. Role of sexual activity, reproductive factors, and venereal infections. Cancer Causes Control. 1992; 3(4):339-48. DOI: 10.1007/BF00146887. View

13.

Hansen E . Chest symptoms in chimney sweeps and postmen--a comparative survey. Int J Epidemiol. 1990; 19(2):339-42. DOI: 10.1093/ije/19.2.339. View

14.

Friis S, Storm H . Urban-rural variation in cancer incidence in Denmark 1943-1987. Eur J Cancer. 1993; 29A(4):538-44. DOI: 10.1016/s0959-8049(05)80147-9. View

15.

Ulfvarson U, Alexandersson R, Aringer L, Svensson E, Hedenstierna G, Hogstedt C . Effects of exposure to vehicle exhaust on health. Scand J Work Environ Health. 1987; 13(6):505-12. DOI: 10.5271/sjweh.2012. View

16.

Evans R, Webb K, Homan S, Ayres S . Cross-sectional and longitudinal changes in pulmonary function associated with automobile pollution among bridge and tunnel officers. Am J Ind Med. 1988; 14(1):25-36. DOI: 10.1002/ajim.4700140105. View

17.

Cohen A . Outdoor air pollution and lung cancer. Environ Health Perspect. 2000; 108 Suppl 4:743-50. PMC: 1637685. DOI: 10.1289/ehp.00108s4743. View

18.

Raaschou-Nielsen O, Nielsen M, Gehl J . Traffic-related air pollution: exposure and health effects in Copenhagen street cleaners and cemetery workers. Arch Environ Health. 1995; 50(3):207-13. DOI: 10.1080/00039896.1995.9940389. View

19.

Jongeneelen F, Scheepers P, Groenendijk A, van Aerts L, Anzion R, Bos R . Airborne concentrations, skin contamination, and urinary metabolite excretion of polycyclic aromatic hydrocarbons among paving workers exposed to coal tar derived road tars. Am Ind Hyg Assoc J. 1988; 49(12):600-7. DOI: 10.1080/15298668891380312. View

20.

HERNBERG S . "Negative" results in cohort studies--how to recognize fallacies. Scand J Work Environ Health. 1981; 7 Suppl 4:121-6. View