The Immune Response to AIDS Virus Infection: Good, Bad, or Both?

Overview

Journal J Clin Invest

Specialty General Medicine

Date 2004 Apr 7

PMID 15067312

Citations 32

Authors

Steven G Deeks

Bruce D Walker

Affiliations

Soon will be listed here.

Abstract

A potent antigen-specific T cell response to HIV infection can contribute to the control of viral replication and is therefore beneficial to the host. However, HIV-mediated increases in generalized T cell activation also appear to accelerate both viral replication and CD4+ T cell depletion. A new study in the JCI attempts to experimentally distinguish the beneficial versus harmful aspects of this immune response.

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