Genes Associated with Addiction: Alcoholism, Opiate, and Cocaine Addiction

Overview

Journal Neuromolecular Med

Specialty Biochemistry

Date 2004 Mar 6

PMID 15001815

Citations 49

Authors

Mary Jeanne Kreek

David A Nielsen

K Steven LaForge

Affiliations

Soon will be listed here.

Abstract

Drug addiction is a complex disorder that has a large spectrum of causes. Vulnerability to addiction has been shown in twin studies to have a robust genetic component. This genetic basis for addiction has general and specific components for each drug abused. Although many genes have been implicated in drug addiction, only a handful have either been replicated to have an association or to have an identified functional mechanism related to specific effects of abused drugs. A few selected genetic variants that currently look promising for the study of alcohol, opiate, and cocaine addiction are discussed in this article.

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