Sinus Histiocytosis with Massive Lymphadenopathy Rosai-Dorfman: Three Unusual Manifestations

Overview

Journal Virchows Arch

Specialties Cell Biology
Molecular Biology
Pathology

Date 2004 Feb 6

PMID 14756147

Citations 1

Authors

Gudrun Ratzinger

Bettina Zelger

Walter Hobling

Gregor Mikuz

Bernhard W Zelger

Affiliations

Soon will be listed here.

Abstract

We report on three exceptional courses of sinus histiocytosis Rosai-Dorfman. Patient one developed regional lymph-node disease subsequent to two independent malignancies in the right head and neck region. Patient two suffered from extensive extranodal disease with more than 100 mucocutaneous lesions over 17 years, which spontaneously resolved. Patient three showed exclusively extranodal disease, including bilateral conjunctival/scleral lesions, before he developed lung cancer. Our cases are unique for three reasons: the association of the disease with solid malignancies in two cases, the extent and persistence of exclusively extranodal disease in one patient and the appearance of thus far undescribed conjunctival/scleral lesions.

Citing Articles

An Unusual Case of Extranodal Rosai-Dorfman Disease Manifesting as an Epibulbar Mass.

Tran H, Chinichian S, Storkersen K, Tokuhara K Case Rep Ophthalmol. 2015; 6(3):351-5.

PMID: 26600788 PMC: 4649714. DOI: 10.1159/000440994.

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