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Rosai-Dorfman Disease Presenting with Isolated Bilateral Orbital Masses: Report of Two Cases

Overview
Specialty Neurology
Date 2001 Aug 11
PMID 11498433
Citations 18
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Abstract

Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is a rare benign idiopathic proliferative disease of phagocytic histiocytes. Approximately 80% of patients present with painless massive cervical lymphadenopathy. Isolated extranodal involvement is relatively uncommon. Two cases of Rosai-Dorfman disease are reported: one with isolated bilateral orbital involvement and one with marked cervical lymphadenopathy and multiple dural-based and intraventricular masses.

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