Chromosomes Take the Lead in Spindle Assembly

Overview

Journal Trends Cell Biol

Specialty Cell Biology

Date 1995 Aug 1

PMID 14732087

Citations 27

Authors

I Vernos

E Karsenti

Affiliations

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Abstract

Several kinesin-like motor proteins have recently been found associated with chromosome arms. They seem to be involved in the so-called 'polar ejection forces' that contribute to the congression of chromosomes on the metaphase plate, and at least one of them is essential for the maintenance of spindle bipolarity. The discovery of these molecules changes our view of the mechanism of spindle assembly and chromosome movement.

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