Representing Complexity in Part-whole Relationships Within the Foundational Model of Anatomy

Overview

Journal AMIA Annu Symp Proc

Specialty Medical Informatics

Date 2004 Jan 20

PMID 14728213

Citations 14

Authors

Jose V Mejino Jr

Augusto V Agoncillo

Kurt L Rickard

Cornelius Rosse

Affiliations

Soon will be listed here.

Abstract

The Foundational Model of Anatomy (FMA) is a frame-based ontology that represents declarative knowledge about the structural organization of the human body. Part-whole relationships play a particularly important role in this representation. In order to assure that knowledge-based applications relying on the FMA as a resource can reason about anatomy, we have modified and enhanced currently available schemes of meronymic relationships. We have introduced and defined distinct partitions for decomposing anatomical structures and attributed the part relationships in order to eliminate ambiguity and enhance specificity in the richness of meronymic relationships within the FMA.

Citing Articles

Computational Identification of Gene Networks as a Biomarker of Neuroblastoma Risk.

Sun L, Jiang L, Grant C, Wang H, Gragnoli C, Liu Z Cancers (Basel). 2020; 12(8).

PMID: 32731407 PMC: 7465094. DOI: 10.3390/cancers12082086.

Levels and building blocks-toward a domain granularity framework for the life sciences.

Vogt L J Biomed Semantics. 2019; 10(1):4.

PMID: 30691505 PMC: 6348634. DOI: 10.1186/s13326-019-0196-2.

Human Development Domain of the Ontology of Craniofacial Development and Malformation.

Mejino Jr J, Travillian R, Cox T, Shapiro L, Brinkley J CEUR Workshop Proc. 2017; 1060:74-77.

PMID: 28261023 PMC: 5331931.

Terminology development towards harmonizing multiple clinical neuroimaging research repositories.

Turner J, Pasquerello D, Turner M, Keator D, Alpert K, King M Data Integr Life Sci. 2015; 9162:104-117.

PMID: 26688838 PMC: 4682911. DOI: 10.1007/978-3-319-21843-4_8.

Accommodating ontologies to biological reality--top-level categories of cumulative-constitutively organized material entities.

Vogt L, Grobe P, Quast B, Bartolomaeus T PLoS One. 2012; 7(1):e30004.

PMID: 22253856 PMC: 3253816. DOI: 10.1371/journal.pone.0030004.

References

Rosse C, Mejino J, Modayur B, JAKOBOVITS R, Hinshaw K, Brinkley J . Motivation and organizational principles for anatomical knowledge representation: the digital anatomist symbolic knowledge base. J Am Med Inform Assoc. 1998; 5(1):17-40. PMC: 61273. DOI: 10.1136/jamia.1998.0050017. View

Neal P, Shapiro L, Rosse C . The digital anatomist structural abstraction: a scheme for the spatial description of anatomical entities. Proc AMIA Symp. 1999; :423-7. PMC: 2232159. View

Michael J, Mejino Jr J, Rosse C . The role of definitions in biomedical concept representation. Proc AMIA Symp. 2002; :463-7. PMC: 2243376. View

Rosse C, Mejino Jr J . A reference ontology for biomedical informatics: the Foundational Model of Anatomy. J Biomed Inform. 2004; 36(6):478-500. DOI: 10.1016/j.jbi.2003.11.007. View

Rogers J, Rector A . GALEN's model of parts and wholes: experience and comparisons. Proc AMIA Symp. 2000; :714-8. PMC: 2243933. View