Off to a Good Start: the Influence of Pre- and Periconceptional Exposures, Parental Fertility, and Nutrition on Children's Health

Overview

Journal Environ Health Perspect

Date 2003 Dec 31

PMID 14698934

Citations 33

Authors

Robert E Chapin

Wendie A Robbins

Laura A Schieve

Anne M Sweeney

Sonia A Tabacova

Kay M Tomashek

Affiliations

Soon will be listed here.

Abstract

The scientific community is developing a compelling body of evidence that shows the importance of the in utero environment (including chemical and hormonal levels) to the ultimate health of the child and even of the aging adult. This article summarizes the evidence that shows this impact begins with conception. Only a full life-cycle evaluation will help us understand these impacts, and only such an understanding will produce logically prioritized mitigation strategies to address the greatest threats first. Clearly, the time for analysis begins when the next generation is but a twinkle in the eye.

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References

Susser M, Stein Z . Timing in prenatal nutrition: a reprise of the Dutch Famine Study. Nutr Rev. 1994; 52(3):84-94. DOI: 10.1111/j.1753-4887.1994.tb01395.x. View

Balen A, Tan S, MacDougall J, Jacobs H . Miscarriage rates following in-vitro fertilization are increased in women with polycystic ovaries and reduced by pituitary desensitization with buserelin. Hum Reprod. 1993; 8(6):959-64. DOI: 10.1093/oxfordjournals.humrep.a138174. View

Generoso W, Rutledge J, Cain K, Hughes L, Braden P . Exposure of female mice to ethylene oxide within hours after mating leads to fetal malformation and death. Mutat Res. 1987; 176(2):269-74. DOI: 10.1016/0027-5107(87)90058-3. View

Rothman K, Moore L, Singer M, Nguyen U, Mannino S, Milunsky A . Teratogenicity of high vitamin A intake. N Engl J Med. 1995; 333(21):1369-73. DOI: 10.1056/NEJM199511233332101. View

Kreiss K . Studies on populations exposed to polychlorinated biphenyls. Environ Health Perspect. 1985; 60:193-9. PMC: 1568576. DOI: 10.1289/ehp.8560193. View

Schantz S, Gasior D, Polverejan E, McCaffrey R, Sweeney A, Humphrey H . Impairments of memory and learning in older adults exposed to polychlorinated biphenyls via consumption of Great Lakes fish. Environ Health Perspect. 2001; 109(6):605-11. PMC: 1240343. DOI: 10.1289/ehp.01109605. View

WILKINSON C, Lamb 4th J . The potential health effects of phthalate esters in children's toys: a review and risk assessment. Regul Toxicol Pharmacol. 1999; 30(2 Pt 1):140-55. DOI: 10.1006/rtph.1999.1338. View

Dickey R, Taylor S, Curole D, Rye P, Pyrzak R . Incidence of spontaneous abortion in clomiphene pregnancies. Hum Reprod. 1996; 11(12):2623-8. DOI: 10.1093/oxfordjournals.humrep.a019182. View

Padungtod C, Hassold T, Millie E, Ryan L, Savitz D, Christiani D . Sperm aneuploidy among Chinese pesticide factory workers: scoring by the FISH method. Am J Ind Med. 1999; 36(2):230-8. DOI: 10.1002/(sici)1097-0274(199908)36:2<230::aid-ajim2>3.0.co;2-6. View

10.

Schlebusch H, Wagner U, Van der Ven H, Al-Hasani S, Diedrich K, Krebs D . Polychlorinated biphenyls: the occurrence of the main congeners in follicular and sperm fluids. J Clin Chem Clin Biochem. 1989; 27(9):663-7. DOI: 10.1515/cclm.1989.27.9.663. View

11.

Itikala P, WATKINS M, Mulinare J, Moore C, Liu Y . Maternal multivitamin use and orofacial clefts in offspring. Teratology. 2001; 63(2):79-86. DOI: 10.1002/1096-9926(200102)63:2<79::AID-TERA1013>3.0.CO;2-3. View

12.

Blount B, Silva M, Caudill S, Needham L, Pirkle J, Sampson E . Levels of seven urinary phthalate metabolites in a human reference population. Environ Health Perspect. 2000; 108(10):979-82. PMC: 1240132. DOI: 10.1289/ehp.00108979. View

13.

Sakamoto M, Nakano A, Akagi H . Declining Minamata male birth ratio associated with increased male fetal death due to heavy methylmercury pollution. Environ Res. 2001; 87(2):92-8. DOI: 10.1006/enrs.2001.4293. View

14.

de Beer C, Seibert H . Cadmium, lead, selenium, and zinc in semen of occupationally unexposed men. Andrologia. 1993; 25(1):7-12. DOI: 10.1111/j.1439-0272.1993.tb02674.x. View

15.

Jacobson J, Jacobson S . Intellectual impairment in children exposed to polychlorinated biphenyls in utero. N Engl J Med. 1996; 335(11):783-9. DOI: 10.1056/NEJM199609123351104. View

16.

Xu B, Chia S, Tsakok M, Ong C . Trace elements in blood and seminal plasma and their relationship to sperm quality. Reprod Toxicol. 1993; 7(6):613-8. DOI: 10.1016/0890-6238(93)90038-9. View

17.

MacGillivray I . Epidemiology of twin pregnancy. Semin Perinatol. 1986; 10(1):4-8. View

18.

Colon I, Caro D, Bourdony C, Rosario O . Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development. Environ Health Perspect. 2000; 108(9):895-900. PMC: 2556932. DOI: 10.1289/ehp.108-2556932. View

19.

Fraga C, Motchnik P, Wyrobek A, Rempel D, Ames B . Smoking and low antioxidant levels increase oxidative damage to sperm DNA. Mutat Res. 1996; 351(2):199-203. DOI: 10.1016/0027-5107(95)00251-0. View

20.

Stevens-Simon C, McAnarney E, COULTER M . How accurately do pregnant adolescents estimate their weight prior to pregnancy?. J Adolesc Health Care. 1986; 7(4):250-4. DOI: 10.1016/s0197-0070(86)80017-1. View