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The Pfam Protein Families Database

Overview
Journal Nucleic Acids Res
Publisher Oxford University Press
Specialty Biochemistry
Date 2003 Dec 19
PMID 14681378
Citations 1612
Authors
Alex Bateman
Lachlan Coin
Richard Durbin
Robert D Finn
Volker Hollich
Sam Griffiths-Jones
Ajay Khanna
Mhairi Marshall
Simon Moxon
Erik L L Sonnhammer
David J Studholme
Corin Yeats
Sean R Eddy
Affiliations
Soon will be listed here.
Abstract

Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described. Other recent innovations include modelling of discontinuous domains allowing Pfam domain definitions to be closer to those found in structure databases. Pfam is available on the web in the UK (http://www.sanger.ac.uk/Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://Pfam.cgb.ki.se/).

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