Clinical Evaluation of a Breathing Protocol for PET/CT

Overview

Journal Eur Radiol

Specialty Radiology

Date 2003 Dec 17

PMID 14676976

Citations 18

Authors

Ramon De Juan

Burkhardt Seifert

Thomas Berthold

Gustav K von Schulthess

Gerhard W Goerres

Affiliations

Soon will be listed here.

Abstract

The aim of this study was to assess the frequency and severity of respiration-induced curvilinear respiration artifacts (RICA) on co-registered positron emission tomography/computed tomography (PET/CT) images acquired on a combined PET/CT scanner before and after modifying the respiration protocol for CT scanning, with retrospective analysis of two groups of 100 patients each, before and after implementing a respiration protocol with breath-hold (BH) in the normal expiration position for the acquisition of the CT images. The CT data were used as attenuation map and for image co-registration. A ranking of co-registered PET/CT and PET images (including maximum intensity projection) was done by two observers in consensus using a scale from 0 to 3. Zero indicated that no RICA was visible and 1, 2, and 3 described artifact with increasing severity. A significant difference in RICA occurrence was found between the two groups ( p<0.0001). There was a 45% decrease of artifact frequency when using the normal expiration protocol and a 68% decrease of grade-2 and grade-3 artifacts ( p=0.004). The results of this study suggest that BH during the normal expiration position for CT scanning can be recommended to reduce the occurrence and the severity of RICA on PET/CT.

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References

Burger C, Goerres G, Schoenes S, Buck A, Lonn A, von Schulthess G . PET attenuation coefficients from CT images: experimental evaluation of the transformation of CT into PET 511-keV attenuation coefficients. Eur J Nucl Med Mol Imaging. 2002; 29(7):922-7. DOI: 10.1007/s00259-002-0796-3. View

Osman M, Cohade C, Nakamoto Y, Marshall L, Leal J, Wahl R . Clinically significant inaccurate localization of lesions with PET/CT: frequency in 300 patients. J Nucl Med. 2003; 44(2):240-3. View

Beyer T, Antoch G, Blodgett T, Freudenberg L, Akhurst T, Mueller S . Dual-modality PET/CT imaging: the effect of respiratory motion on combined image quality in clinical oncology. Eur J Nucl Med Mol Imaging. 2003; 30(4):588-96. DOI: 10.1007/s00259-002-1097-6. View

Nakamoto Y, Tatsumi M, Cohade C, Osman M, Marshall L, Wahl R . Accuracy of image fusion of normal upper abdominal organs visualized with PET/CT. Eur J Nucl Med Mol Imaging. 2003; 30(4):597-602. DOI: 10.1007/s00259-002-1080-2. View

Goerres G, Kamel E, Seifert B, Burger C, Buck A, Hany T . Accuracy of image coregistration of pulmonary lesions in patients with non-small cell lung cancer using an integrated PET/CT system. J Nucl Med. 2002; 43(11):1469-75. View