Neurogenesis and the Cell Cycle

Overview

Journal Neuron

Publisher Cell Press

Specialty Neurology

Date 2003 Oct 15

PMID 14556704

Citations 107

Authors

Shin-ichi Ohnuma

William A Harris

Affiliations

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Abstract

For a long time, it has been understood that neurogenesis is linked to proliferation and thus to the cell cycle. Recently, the gears that mediate this linkage have become accessible to molecular investigation. This review describes some of the progress that has been made in understanding how the molecular machinery of the cell cycle is used in the processes of size regulation in the brain, histogenesis, neuronal differentiation, and the maintenance of stem cells.

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