» Articles » PMID: 1455506

G Proteins

Overview
Specialty Biochemistry
Date 1992 Oct 1
PMID 1455506
Citations 239
Authors
Affiliations
Soon will be listed here.
Abstract

The family of heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) serves an essential role in transducing receptor-generated signals across the plasma membrane. Recent findings reveal unexpected functional roles for individual G protein subunits. Thus, GTP-binding alpha-subunits and the beta gamma-subunit complex can influence the activity of effector molecules independently or simultaneously, either synergistically or in opposition, to elicit a complex constellation of cellular events.

Citing Articles

Biased Opioid Receptor Agonists: Balancing Analgesic Efficacy and Side-Effect Profiles.

Ju J, Li Z, Liu J, Peng X, Gao F Int J Mol Sci. 2025; 26(5).

PMID: 40076488 PMC: 11899445. DOI: 10.3390/ijms26051862.


Germline deletion of Rgs2 and/or Rgs5 in male mice does not exacerbate left ventricular remodeling induced by subchronic isoproterenol infusion.

Dahlen S, Mohanty I, Sun B, Nallapaneni S, Osei-Owusu P Physiol Rep. 2025; 13(1):e70178.

PMID: 39746869 PMC: 11695115. DOI: 10.14814/phy2.70178.


Microarray Analysis of Visceral Adipose Tissue in Obese Women Reveals Common Crossroads Among Inflammation, Metabolism, Addictive Behaviors, and Cancer: AKT3 and MAPK1 Cross Point in Obesity.

Martinez-Romero R, Gonzalez-Chavez S, Urias-Rubi V, Gomez-Moreno V, Blanco-Cantero M, Bernal-Velazquez H J Obes. 2024; 2024:4541071.

PMID: 39484291 PMC: 11527533. DOI: 10.1155/2024/4541071.


ProSol-multi: Protein solubility prediction via amino acids multi-level correlation and discriminative distribution.

Ghafoor H, Asim M, Ibrahim M, Dengel A Heliyon. 2024; 10(17):e36041.

PMID: 39281576 PMC: 11401092. DOI: 10.1016/j.heliyon.2024.e36041.


An endothelial regulatory module links blood pressure regulation with elite athletic performance.

Fegraeus K, Rosengren M, Naboulsi R, Orlando L, Abrink M, Jouni A PLoS Genet. 2024; 20(6):e1011285.

PMID: 38885195 PMC: 11182536. DOI: 10.1371/journal.pgen.1011285.