Control of Isoleucine, Valine, and Leucine Biosynthesis. I. Multivalent Repression

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1962 Oct 15

PMID 13959618

Citations 116

Authors

M Freundlich

R O BURNS

H E Umbarger

Affiliations

Soon will be listed here.

Citing Articles

Blocking the 2,3-butanediol synthesis pathway of Klebsiella pneumoniae resulted in L-valine production.

Wang Q, Gu J, Shu L, Jiang W, Mojovic L, Knezevic-Jugovic Z World J Microbiol Biotechnol. 2022; 38(5):81.

PMID: 35348886 DOI: 10.1007/s11274-022-03266-9.

Improving yields of deuterated, methyl labeled protein by growing in HO.

OBrien E, Lin D, Fuglestad B, Stetz M, Gosse T, Tommos C J Biomol NMR. 2018; 71(4):263-273.

PMID: 30073492 PMC: 6165672. DOI: 10.1007/s10858-018-0200-7.

Reconstructed Ancestral Enzymes Impose a Fitness Cost upon Modern Bacteria Despite Exhibiting Favourable Biochemical Properties.

Hobbs J, Prentice E, Groussin M, Arcus V J Mol Evol. 2015; 81(3-4):110-20.

PMID: 26349578 DOI: 10.1007/s00239-015-9697-5.

Prolonged antibiotic use induces intestinal injury in mice that is repaired after removing antibiotic pressure: implications for empiric antibiotic therapy.

Romick-Rosendale L, Legomarcino A, Patel N, Morrow A, Kennedy M Metabolomics. 2015; 10(1):8-20.

PMID: 26273236 PMC: 4532301. DOI: 10.1007/s11306-013-0546-5.

Isolation and cryopreservation of O-methylthreonine-resistant Rosa cell lines altered in the feedback sensitivity of L-threonine deaminase.

Strauss A, Fankhauser H, King P Planta. 2013; 163(4):554-62.

PMID: 24249455 DOI: 10.1007/BF00392713.

References

Leavitt R, Umbarger H . Isoleucine and valine metabolism in Escherichia coli. XI. Valine inhibition of the growth of Escherichia coli strain K-12. J Bacteriol. 1962; 83:624-30. PMC: 279321. DOI: 10.1128/jb.83.3.624-630.1962. View

MYERS J, Adelberg E . THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. I. ENZYMATIC TRANSFORMATION OF THE DIHYDROXY ACID PRECURSORS TO THE KETO ACID PRECURSORS. Proc Natl Acad Sci U S A. 1954; 40(6):493-9. PMC: 534077. DOI: 10.1073/pnas.40.6.493. View

Leavitt R, Umbarger H . Isoleucine and valine metabolism in Escherichia coli. X. The enzymatic formation of acetohydroxybutyrate. J Biol Chem. 1961; 236:2486-91. View

Umbarger H, Brown B . Isoleucine and valine metabolism in Escherichia coli. VII. A negative feedback mechanism controlling isoleucine biosynthesis. J Biol Chem. 1958; 233(2):415-20. View

Novick A, Szilard L . Description of the chemostat. Science. 1950; 112(2920):715-6. DOI: 10.1126/science.112.2920.715. View