» Articles » PMID: 13899115

The Role of Interferon in Vaccinia Virus Infection of Mouse Embryo Tissue Culture

Overview
Journal J Exp Med
Date 1962 Mar 1
PMID 13899115
Citations 31
Authors
Affiliations
Soon will be listed here.
Abstract

The production of an interferon-like substance by vaccinia virus is described. The physical properties of vaccinia interferon are shown to be similar to those of previously reported interferons. Data defining the role of vaccinia interferon in cell resistance and in establishment and maintenance of a carrier culture are presented. Elimination of virus from an infected culture is demonstrated and the role of interferon in the recovery process is considered.

Citing Articles

The emerging role of nuclear viral DNA sensors.

Diner B, Lum K, Cristea I J Biol Chem. 2015; 290(44):26412-21.

PMID: 26354430 PMC: 4646299. DOI: 10.1074/jbc.R115.652289.


Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination.

Jounai N, Kobiyama K, Takeshita F, Ishii K Front Cell Infect Microbiol. 2013; 2:168.

PMID: 23316484 PMC: 3539075. DOI: 10.3389/fcimb.2012.00168.


Antiviral Action of Interferon.

Isaacs A Br Med J. 2010; 2(5301):353-5.

PMID: 20789476 PMC: 1925763. DOI: 10.1136/bmj.2.5301.353.


Initiation of primary anti-vaccinia virus immunity in vivo.

Fischer M, Norbury C Immunol Res. 2007; 37(2):113-33.

PMID: 17695247 DOI: 10.1007/BF02685894.


Persistent Herpes Simplex Virus Infection In Vitro with Cycles of Cell Destruction and Regrowth.

Hampar B, Copeland M J Bacteriol. 1965; 90(1):205-12.

PMID: 16562018 PMC: 315614. DOI: 10.1128/jb.90.1.205-212.1965.


References
1.
Ho M . Inhibition of the infectivity of poliovirus ribonucleic acid by an interferon. Proc Soc Exp Biol Med. 1961; 107:639-44. DOI: 10.3181/00379727-107-26712. View

2.
Henle W, Henle G, Deinhardt F, Bergs V . Studies on persistent infections of tissue cultures. IV. Evidence for the production of an interferon in MCN cells by myxoviruses. J Exp Med. 1959; 110:525-41. PMC: 2136997. DOI: 10.1084/jem.110.4.525. View

3.
Isaacs A, PORTERFIELD J, Baron S . The influence of oxygenation on virus growth. II. Effect on the antiviral action of interferon. Virology. 1961; 14:450-5. DOI: 10.1016/0042-6822(61)90337-3. View

4.
Isaacs A, Burke D, FADEEVA L . Effect of interferon on the growth of viruses on the chick chorion. Br J Exp Pathol. 1958; 39(5):447-51. PMC: 2082254. View

5.
Ho M, ENDERS J . AN INHIBITOR OF VIRAL ACTIVITY APPEARING IN INFECTED CELL CULTURES. Proc Natl Acad Sci U S A. 1959; 45(3):385-9. PMC: 222571. DOI: 10.1073/pnas.45.3.385. View