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GABAA Receptor Channels: from Subunits to Functional Entities

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Specialties Biology
Neurology
Date 1992 Jun 1
PMID 1379501
Citations 43
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Abstract

GABAA receptor channels mediate postsynaptic inhibition. The functional diversity of these receptors rests on differences in subunit composition and on a large repertoire of subunits. Subunit expression patterns in the brain have been found to predict in vivo compositions of GABAA receptors. In addition, molecular determinants underlying the differential binding properties of allosteric ligands to receptor subtypes have been identified.

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