Physical and Biological Properties of Influenza Virus Components Obtained After Ether Treatment

Overview

Journal J Exp Med

Specialties Allergy & Immunology
General Medicine

Date 1960 Nov 1

PMID 13719952

Citations 46

Authors

F M DAVENPORT

R Rott

W Schaefer

Affiliations

Soon will be listed here.

Abstract

The Rostock strain of fowl plague, the swine, A, A', and Asian strains of influenza A as well as their hemagglutinin and internal s antigen subunits obtained after ether splitting, were found to be morphologically indistinguishable when examined simultaneously. Hemagglutinin fractions reacted in a highly strain specific manner when tested by hemagglutination inhibition or by complement fixation using sera obtained after infection. With the same sera internal s antigen fractions were shown to be serologically distinguishable by complement fixation. This observation may stimulate interest in the feasibility of employing immunologic techniques for the study of nucleoproteins. The significance of the findings reported is discussed.

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METHODS OF DETERMINING IMMUNITY, DURATION AND CHARACTER OF IMMUNITY RESULTING FROM MEASLES.

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