Frequencies of X-ray-induced Chromosome Translocations in Human Peripheral Lymphocytes As Detected by in Situ Hybridization Using Chromosome-specific DNA Libraries

Overview

Journal Int J Radiat Biol

Specialty Radiology

Date 1992 Feb 1

PMID 1351907

Citations 17

Authors

A T Natarajan

R C Vyas

F Darroudi

S Vermeulen

Affiliations

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Abstract

In situ hybridization with chromosome-specific DNA libraries was used to analyse radiation-induced stable translocations in human peripheral blood lymphocytes. These data were compared with radiation-induced unstable-type aberrations (dicentrics) in the same samples. The results indicate that far more stable aberrations are induced by radiation in comparison to unstable aberrations.

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