17-Hydroxycorticosteroid Metabolism in Liver Disease

Overview

Journal J Clin Invest

Specialty General Medicine

Date 1954 Nov 1

PMID 13211807

Citations 40

Authors

H Brown

D G WILLARDSON

L T SAMUELS

F H TYLER

Affiliations

Soon will be listed here.

Citing Articles

Decreased maximal cortisol secretion rate in patients with cirrhosis: Relation to disease severity.

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Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis.

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CORTISOL METABOLISM IN MAN: OBSERVATIONS OF PATHWAYS, POOL SIZES OF METABOLITES AND RATES OF FORMATION OF METABOLITES.

Gold N, Smith L, MOORE F J Clin Invest. 1959; 38(12):2238-52.

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[On the problem of the effect of phenylbutazone on the function of the adrenal cortex and on the biological half-life of cortisol].

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[Corticosteroid catabolism and liver function in healthy subjects and in those with liver diseases].

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References

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EIK-NES K, Nelson D, SAMUELS L . Determination of 17,21-hydroxycorticosteroids in plasma. J Clin Endocrinol Metab. 1953; 13(10):1280-2. DOI: 10.1210/jcem-13-10-1280. View

Sayers G . The adrenal cortex and homoestasis. Physiol Rev. 1950; 30(3):241-320. DOI: 10.1152/physrev.1950.30.3.241. View

Nelson D, SAMUELS L . A method for the determination of 17-hydroxycorticosteroids in blood; 17-hydroxycorticosterone in the peripheral circulation. J Clin Endocrinol Metab. 1952; 12(5):519-26. DOI: 10.1210/jcem-12-5-519. View

EIK-NES K, Sandberg A, Nelson D, TYLER F, SAMUELS L . Changes in plasma levels of 17-hydroxycorticosteroids during the intravenous administration of ACTH. I. A test of adrenocortical capacity in the human. J Clin Invest. 1954; 33(11):1502-8. PMC: 1072575. DOI: 10.1172/JCI103028. View

REDDY W, Jenkins D, Thorn G . Estimation of 17-hydroxycorticoids in urine. Metabolism. 1952; 1(6):511-27. View

TYLER F, SCHMIDT C, EIK-NES K, Brown H, SAMUELS L . The role of the liver and the adrenal in producing elevated plasma 17-hydroxycorticosteroid levels in surgery. J Clin Invest. 1954; 33(11):1517-23. PMC: 1072577. DOI: 10.1172/JCI103030. View

SAMUELS L, WEST C . The intermediary metabolism of the non-benzenoid steroid hormones. Vitam Horm. 1952; 10:251-95. DOI: 10.1016/s0083-6729(08)60849-3. View

KARK R, KEETON R, Calloway N, MOREY G, Chapman R, KYLE R . A rational basis for the use of low sodium, high protein diet therapy in Laennec's cirrhosis. AMA Arch Intern Med. 1951; 88(1):61-77. DOI: 10.1001/archinte.1951.03810070071009. View

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Goldman R, Bassett S . Diurnal variation in the urinary excretion of neutral lipid-soluble reducing steroids in congestive cardiac failure and cirrhosis of the liver with ascites. J Clin Invest. 1952; 31(3):253-8. PMC: 436409. DOI: 10.1172/JCI102600. View

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Sandberg A, EIK-NES K, SAMUELS L, TYLER F . The effects of surgery on the blood levels and metabolism of 17-hydroxycorticosteroids in man. J Clin Invest. 1954; 33(11):1509-16. PMC: 1072576. DOI: 10.1172/JCI103029. View

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Bongiovanni A, EISENMENGER W . Adrenal cortical metabolism in chronic liver disease. J Clin Endocrinol Metab. 1951; 11(2):152-72. DOI: 10.1210/jcem-11-2-152. View

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Baggett B, KINSELLA Jr R, Doisy E . Hydrolysis of conjugates of urinary corticoids with beta-glucuronidase. II. The isolation and determination of tetrahydrocortisone. J Biol Chem. 1953; 203(2):1013-22. View