Cross Bridge ATP Utilization in Arterial Smooth Muscle

Overview

Journal Pflugers Arch

Specialty Physiology

Date 1976 Feb 24

PMID 130614

Citations 9

Authors

R J Paul

E Gluck

J C Ruegg

Affiliations

Soon will be listed here.

Abstract

Measurements of oxygen consumption and lactate production were used to estimate the ATP production in porcine carotid arteries. Changes in the total energy metabolism were correlated with changes in force which was altered by changing the muscle length under maximum stimulation. This tension-dependent metabolism could be used to distinguish between cross bridge and other ATP utilization. The tension-dependent metabolism was equal under K+ -depolarization or histamine stimulation. Tension cost was 300x smaller than skeletal muscle while the cross bridge cycle duration 30x longer.

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