» Articles » PMID: 12967967

MedScan, a Natural Language Processing Engine for MEDLINE Abstracts

Overview
Journal Bioinformatics
Specialty Biology
Date 2003 Sep 12
PMID 12967967
Citations 67
Authors
Affiliations
Soon will be listed here.
Abstract

Motivation: The importance of extracting biomedical information from scientific publications is well recognized. A number of information extraction systems for the biomedical domain have been reported, but none of them have become widely used in practical applications. Most proposals to date make rather simplistic assumptions about the syntactic aspect of natural language. There is an urgent need for a system that has broad coverage and performs well in real-text applications.

Results: We present a general biomedical domain-oriented NLP engine called MedScan that efficiently processes sentences from MEDLINE abstracts and produces a set of regularized logical structures representing the meaning of each sentence. The engine utilizes a specially developed context-free grammar and lexicon. Preliminary evaluation of the system's performance, accuracy, and coverage exhibited encouraging results. Further approaches for increasing the coverage and reducing parsing ambiguity of the engine, as well as its application for information extraction are discussed.

Citing Articles

A Computational Protocol for the Knowledge-Based Assessment and Capture of Pathologies.

Page J, Moore N, Broderick G Methods Mol Biol. 2024; 2868:265-284.

PMID: 39546235 DOI: 10.1007/978-1-0716-4200-9_14.


Sex-Specific Skeletal Muscle Gene Expression Responses to Exercise Reveal Novel Direct Mediators of Insulin Sensitivity Change.

Ma S, Morris M, Hubal M, Ross L, Huffman K, Vann C medRxiv. 2024; .

PMID: 39281755 PMC: 11398589. DOI: 10.1101/2024.09.07.24313236.


Crosstalk between short- and long-term calorie restriction transcriptomic signatures with anxiety-like behavior, aging, and neurodegeneration: implications for drug repurposing.

Hazi A, Ebrahimie E, Levay E, Mohammadi-Dehcheshmeh M, Zelko M, Govic A Front Behav Neurosci. 2023; 17:1257881.

PMID: 38094940 PMC: 10716537. DOI: 10.3389/fnbeh.2023.1257881.


A regulatory pathway model of neuropsychological disruption in Havana syndrome.

Chacko T, Toole J, Morris M, Page J, Forsten R, Barrett J Front Psychiatry. 2023; 14:1180929.

PMID: 37965360 PMC: 10642174. DOI: 10.3389/fpsyt.2023.1180929.


Automated assembly of molecular mechanisms at scale from text mining and curated databases.

Bachman J, Gyori B, Sorger P Mol Syst Biol. 2023; 19(5):e11325.

PMID: 36938926 PMC: 10167483. DOI: 10.15252/msb.202211325.