» Articles » PMID: 129020

A Gentamycin Resistance Plasmid in Staphylococcus Aureus

Overview
Specialty Microbiology
Date 1975 Jul 1
PMID 129020
Citations 14
Authors
Affiliations
Soon will be listed here.
Abstract

Drug resistance in Staphylococcus aureus is frequently mediated by non-chromosomal DNA molecules referred to as R plasmids. So far, resistance to aminosidic antibiotics was observed with streptomycin [8] and kanamycin-neomycin [3]. Resistance to gentamycin has not been reported in a recent survey by Lacey [7]. In this paper, we describe a strain of S. aureus resistant to gentamycin-kanamycin-tobramycin-sisomycin, and experiments which suggest that the genetic determinant of these resistance characters is plasmid borne.

Citing Articles

Molecular Basis of Non-β-Lactam Antibiotics Resistance in .

Lade H, Joo H, Kim J Antibiotics (Basel). 2022; 11(10).

PMID: 36290036 PMC: 9598170. DOI: 10.3390/antibiotics11101378.


Antimicrobial susceptibility of coagulase-negative staphylococci.

Archer G, Climo M Antimicrob Agents Chemother. 1994; 38(10):2231-7.

PMID: 7840550 PMC: 284723. DOI: 10.1128/AAC.38.10.2231.


Aminocyclitol-modifying enzymes specified by chromosomal genes in Staphylococcus aureus.

Kayser F, HOMBERGER F, Devaud M Antimicrob Agents Chemother. 1981; 19(5):766-72.

PMID: 6271046 PMC: 181519. DOI: 10.1128/AAC.19.5.766.


Cefotaxime in combination with other antibiotics for the treatment of severe methicillin-resistant staphylococcal infections.

Portier H, Kazmierczak A, Lucht F, Tremeaux J, Chavanet P, Duez J Infection. 1985; 13 Suppl 1:S123-8.

PMID: 3850854 DOI: 10.1007/BF01644232.


Antimicrobial resistance of Staphylococcus aureus: genetic basis.

Lyon B, Skurray R Microbiol Rev. 1987; 51(1):88-134.

PMID: 3031442 PMC: 373094. DOI: 10.1128/mr.51.1.88-134.1987.