Ceftriaxone-associated Nephrolithiasis and Biliary Pseudolithiasis in a Child

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 2003 Jun 28

PMID 12830336

Citations 23

Authors

Jeffrey S Prince

Melvin O Senac Jr

Affiliations

Soon will be listed here.

Abstract

Ceftriaxone is a widely used third-generation cephalosporin. It is generally very safe, but complications of biliary pseudolithiasis and, rarely, nephrolithiasis have been reported in children. These complications generally resolve spontaneously with cessation of the ceftriaxone therapy; however, they may symptomatically mimic more serious clinical problems, such as cholecystitis. We report a case of both ceftriaxone-induced biliary pseudolithiasis and nephrolithiasis.

Citing Articles

Cefotaxime Versus Ceftriaxone: A Comprehensive Comparative Review.

Sharma B, Chalikwar R, Bhalerao S, Gondane A, Pawar D, Sharma A Cureus. 2024; 16(9):e69146.

PMID: 39398799 PMC: 11467699. DOI: 10.7759/cureus.69146.

Nephrotoxicity of Amoxicillin and Third-Generation Cephalosporins: An Updated Review.

Garnier A, Drablier G, Briet M, Augusto J Drug Saf. 2023; 46(8):715-724.

PMID: 37310614 DOI: 10.1007/s40264-023-01316-1.

Ceftriaxone Administration Associated with Lithiasis in Children: Guilty or Not? A Systematic Review.

Louta A, Kanellopoulou A, Alexopoulou Prounia L, Filippas M, Tsami F, Vlachodimitropoulos A J Pers Med. 2023; 13(4).

PMID: 37109057 PMC: 10142585. DOI: 10.3390/jpm13040671.

Asymptomatic Cholelithiasis in Children: Management Dilemma.

Bhaumik K J Indian Assoc Pediatr Surg. 2021; 26(4):228-233.

PMID: 34385765 PMC: 8323576. DOI: 10.4103/jiaps.JIAPS_107_20.

Computed tomography findings of ceftriaxone-associated biliary pseudocholelithiasis in adults.

Yoshida R, Yoshizako T, Katsube T, Kitagaki H Jpn J Radiol. 2019; 37(12):826-831.

PMID: 31654330 DOI: 10.1007/s11604-019-00893-5.

References

Schaad U, Tschaeppeler H . Reversible ceftriaxone-associated biliary pseudolithiasis in children. Lancet. 1988; 2(8625):1411-3. DOI: 10.1016/s0140-6736(88)90596-x. View

Grasberger H, Otto B, Loeschke K . Ceftriaxone-associated nephrolithiasis. Ann Pharmacother. 2000; 34(9):1076-7. DOI: 10.1345/aph.19363. View

Maranan M, Gerber S, Miller G . Gallstone pancreatitis caused by ceftriaxone. Pediatr Infect Dis J. 1998; 17(7):662-3. DOI: 10.1097/00006454-199807000-00022. View

Bonnet J, Abid L, Dabhar A, Levy A, Soulier Y, Blangy S . Early biliary pseudolithiasis during ceftriaxone therapy for acute pyelonephritis in children: a prospective study in 34 children. Eur J Pediatr Surg. 2001; 10(6):368-71. DOI: 10.1055/s-2008-1072393. View

Palanduz A, Yalcin I, Tonguc E, Guler N, Ones U, Salman N . Sonographic assessment of ceftriaxone-associated biliary pseudolithiasis in children. J Clin Ultrasound. 2001; 28(4):166-8. DOI: 10.1002/(sici)1097-0096(200005)28:4<166::aid-jcu2>3.0.co;2-g. View