Profiling Breast Cancer by Array CGH

Overview

Journal Breast Cancer Res Treat

Specialty Oncology

Date 2003 May 21

PMID 12755488

Citations 26

Authors

Donna G Albertson

Affiliations

Soon will be listed here.

Abstract

Breast tumors display a wide variety of genomic alterations. This review focuses on DNA copy number variations in these tumors as measured by the recently developed microarray-based form of comparative genomic hybridization. The capabilities of this new technology are reviewed. Initial applications of array CGH to the analysis of breast cancer, and the mechanisms by which the particular types of copy number changes might arise are discussed.

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