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Elevated Fecal Candida Counts in Patients with Antibiotic-associated Diarrhea: Role of Soluble Fecal Substances

Overview
Journal Clin Diagn Lab Immunol
Publisher American Society for Microbiology
Specialty Allergy & Immunology
Date 2003 Jan 11
PMID 12522055
Citations 5
Authors
Robert Krause
Gunter J Krejs
Christoph Wenisch
Emil C Reisinger
Affiliations
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Abstract

To assess the role of soluble fecal substances in the elevation of fecal Candida counts in patients with antibiotic-associated diarrhea (AAD), we investigated the growth of Candida albicans in vitro in serially diluted stool fluids from patients with AAD and healthy subjects. There were significantly higher Candida albicans counts in stool fluids diluted 1:10 from AAD patients than in healthy subjects and the phosphate-buffered saline growth control, which may be due to reduced soluble Candida inhibitors and increased availability of growth factors and nutrients.

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