Navigating the Signalling Network in Mouse Cardiac Myocytes

Overview

Journal Nature

Specialty Science

Date 2002 Dec 13

PMID 12478303

Citations 34

Authors

Gilberto R Sambrano

Iain Fraser

Heping Han

Yan Ni

Tim OConnell

Zhen Yan

James T Stull

Affiliations

Soon will be listed here.

Abstract

Cardiac myocytes have a complex network of signals that regulates their essential role in the rhythmic pumping of the heart. This network is an appealing model system in which to study the basic principles underlying cellular signalling mechanisms. Progress in this effort has come through the establishment of standardized myocyte isolation and culture procedures and characterization of important signalling responses.

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