Genetics of Resistance to Colicins in Escherichia Coli K-12: Cross-resistance Among Colicins of Group B

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1975 Jul 1

PMID 124727

Citations 95

Authors

J K Davies

P Reeves

Affiliations

Soon will be listed here.

Abstract

This paper describes the isolation of mutants resistant to colicins of group B (i.e., colicins B, D, G, H, Ia, Ib, M, Q, S1, and V). The 145 mutants studied in detail can be divided into nine phentopyic classes, based on their colicin-resistance patterns. They include the previously isolated tonA, tonB exbB and cir mutants. Each of the different phenotypic classes of mutants has been partially characterized, and some approximately mapped. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis has revealed substantial changes in the composition of the outer membrane proteins of exbB and tonB mutants.

Citing Articles

The Tol Pal system integrates maintenance of the three layered cell envelope.

Szczepaniak J, Webby M NPJ Antimicrob Resist. 2025; 2(1):46.

PMID: 39843782 PMC: 11721397. DOI: 10.1038/s44259-024-00065-0.

Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition.

Halvorsen T, Schroeder K, Jones A, Hammarlof D, Low D, Koskiniemi S PLoS Genet. 2024; 20(11):e1011494.

PMID: 39591464 PMC: 11630599. DOI: 10.1371/journal.pgen.1011494.

Story of Pore-Forming Proteins from Deadly Disease-Causing Agents to Modern Applications with Evolutionary Significance.

Gupta L, Molla J, Prabhu A Mol Biotechnol. 2023; 66(6):1327-1356.

PMID: 37294530 DOI: 10.1007/s12033-023-00776-1.

Iron Acquisition Systems of Gram-negative Bacterial Pathogens Define TonB-Dependent Pathways to Novel Antibiotics.

Klebba P, Newton S, Six D, Kumar A, Yang T, Nairn B Chem Rev. 2021; 121(9):5193-5239.

PMID: 33724814 PMC: 8687107. DOI: 10.1021/acs.chemrev.0c01005.

Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins.

Shushan A, Kosloff M Sci Rep. 2021; 11(1):3789.

PMID: 33589691 PMC: 7884437. DOI: 10.1038/s41598-021-83265-2.

References

Davies J, Reeves P . Genetics of resistance to colicins in Escherichia coli K-12: cross-resistance among colicins of group A. J Bacteriol. 1975; 123(1):102-17. PMC: 235696. DOI: 10.1128/jb.123.1.102-117.1975. View

FREDERICQ P . [Research on the character and distribution of bacterial strains producing various types of colicin in normal and pathological feces]. Bull Acad R Med Belg. 1953; 18(2):126-39. View

GRATIA J . [RESISTANCE TO COLICIN B IN ESCHERICHIA COLI. SPECIFICITY RELATIONS AMONG COLICINS B, I AND V AND PHAGE T-4. GENETIC STUDY]. Ann Inst Pasteur (Paris). 1964; 107:SUPPL:132-51. View

CURTIS 3rd S . CHROMOSOMAL ABERRATIONS ASSOCIATED WITH MUTATIONS TO BACTERIOPHAGE RESISTANCE IN ESCHERICHIA COLI. J Bacteriol. 1965; 89:28-40. PMC: 315544. DOI: 10.1128/JB.89.1.28-40.1965. View

FREDERICQ P . [Spontaneous formation of the colicine M producing mutants of Esch. coli V]. Antonie Van Leeuwenhoek. 1951; 17(4):227-31. DOI: 10.1007/BF02062267. View

Swank R, MUNKRES K . Molecular weight analysis of oligopeptides by electrophoresis in polyacrylamide gel with sodium dodecyl sulfate. Anal Biochem. 1971; 39(2):462-77. DOI: 10.1016/0003-2697(71)90436-2. View

Taylor A, Trotter C . Linkage map of Escherichia coli strain K-12. Bacteriol Rev. 1972; 36(4):504-24. PMC: 408330. DOI: 10.1128/br.36.4.504-524.1972. View

Guterman S . Colicin B: mode of action and inhibition by enterochelin. J Bacteriol. 1973; 114(3):1217-24. PMC: 285385. DOI: 10.1128/jb.114.3.1217-1224.1973. View

Guterman S, Dann L . Excretion of enterochelin by exbA and exbB mutants of Escherichia coli. J Bacteriol. 1973; 114(3):1225-30. PMC: 285386. DOI: 10.1128/jb.114.3.1225-1230.1973. View

10.

Braun V, Wolff H . Characterization of the receptor protein for phage T5 and colicin M in the outer membrane of E. coli B. FEBS Lett. 1973; 34(1):77-80. DOI: 10.1016/0014-5793(73)80707-0. View

11.

Schnaitman C . Outer membrane proteins of Escherichia coli. I. Effect of preparative conditions on the migration of protein in polyacrylamide gels. Arch Biochem Biophys. 1973; 157(2):541-52. DOI: 10.1016/0003-9861(73)90673-5. View

12.

Braun V, Schaller K, Wolff H . A common receptor protein for phage T5 and colicin M in the outer membrane of Escherichia coli B. Biochim Biophys Acta. 1973; 323(1):87-97. DOI: 10.1016/0005-2736(73)90433-1. View

13.

Cardelli J, Konisky J . Isolation and characterization of an Escherichia coli mutant tolerant to colicins Ia and Ib. J Bacteriol. 1974; 119(2):379-85. PMC: 245618. DOI: 10.1128/jb.119.2.379-385.1974. View

14.

Timmis K . Purification and characterization of colicin D. J Bacteriol. 1972; 109(1):12-20. PMC: 247245. DOI: 10.1128/jb.109.1.12-20.1972. View

15.

Schacterle G, POLLACK R . A simplified method for the quantitative assay of small amounts of protein in biologic material. Anal Biochem. 1973; 51(2):654-5. DOI: 10.1016/0003-2697(73)90523-x. View

16.

Guterman S, Luria S . Escherichia coli: strains that excrete an inhibitor of colicin B. Science. 1969; 164(3886):1414. DOI: 10.1126/science.164.3886.1414. View

17.

FREDERICQ P, Smarda J . [Complexity of colicinogenic B factor]. Ann Inst Pasteur (Paris). 1970; 118(6):767-74. View

18.

Schnaitman C . Solubilization of the cytoplasmic membrane of Escherichia coli by Triton X-100. J Bacteriol. 1971; 108(1):545-52. PMC: 247096. DOI: 10.1128/jb.108.1.545-552.1971. View

19.

Guterman S . Inhibition of colicin B by enterochelin. Biochem Biophys Res Commun. 1971; 44(5):1149-55. DOI: 10.1016/s0006-291x(71)80206-1. View

20.

Neville Jr D . Molecular weight determination of protein-dodecyl sulfate complexes by gel electrophoresis in a discontinuous buffer system. J Biol Chem. 1971; 246(20):6328-34. View