Orchestrating the Unfolded Protein Response in Health and Disease

Overview

Journal J Clin Invest

Specialty General Medicine

Date 2002 Nov 20

PMID 12438434

Citations 528

Authors

Randal J Kaufman

Affiliations

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Citing Articles

Endoplasmic Reticulum Stress: Implications in Diseases.

Walter N, Gorki V, Bhardwaj R, Punnakkal P Protein J. 2025; .

PMID: 40082380 DOI: 10.1007/s10930-025-10264-x.

PARP-16 regulates the PERK and IRE-1α Mediated Unfolded Protein Response in Japanese Encephalitis Virus-Infected Neural Stem/Progenitor Cells.

Sharma S, Satheesan A, Majumdar A, Mukherjee S, Basu A Mol Neurobiol. 2025; .

PMID: 39979689 DOI: 10.1007/s12035-025-04748-1.

Regulation of ER stress-induced apoptotic and inflammatory responses via YAP/TAZ-mediated control of the TRAIL-R2/DR5 signaling pathway.

El Yousfi Y, Fernandez-Farran F, Oliver F, Lopez-Rivas A, Yerbes R Cell Death Discov. 2025; 11(1):42.

PMID: 39904986 PMC: 11794427. DOI: 10.1038/s41420-025-02335-w.

Noncanonical UPR factor CREB3L2 drives immune evasion of triple-negative breast cancer through Hedgehog pathway modulation in T cells.

Cao Z, You J, Fan Y, Yang J, Sun J, Ma X Sci Adv. 2025; 11(2):eads5434.

PMID: 39792663 PMC: 11721608. DOI: 10.1126/sciadv.ads5434.

Insights into the molecular underlying mechanisms and therapeutic potential of endoplasmic reticulum stress in sensorineural hearing loss.

Li G, Yang H, Zhang P, Guo Y, Yuan L, Xu S Front Mol Neurosci. 2025; 17:1443401.

PMID: 39744539 PMC: 11688397. DOI: 10.3389/fnmol.2024.1443401.

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