4-[6-(Dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine As a New Potential Fluorescent Probe for Studying A1-adenosine Receptor

Overview

Journal Farmaco

Publisher Elsevier

Specialties Chemistry
Pharmacology

Date 2002 Nov 8

PMID 12420873

Citations 3

Authors

Marco Macchia

Simone Bertini

Valeria Di Bussolo

Clementina Manera

Claudia Martini

Filippo Minutolo

Claudio Mori

Giuseppe Saccomanni

Daniela Tuscano

Pier Luigi Ferrarini

Affiliations

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Abstract

A new fluorescent ligand for adenosine receptors, obtained by the insertion of a dansylamino-moiety with a linear hexyl spacer in the N4 position of a 1,8-naphthyridine adenosine receptor ligand, proved to possess a high affinity and selectivity for the A1 receptor subtype.

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