Saccharomyces Cerevisiae is Permissive for Replication of Bovine Papillomavirus Type 1

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2002 Nov 5

PMID 12414966

Citations 12

Authors

Kong-Nan Zhao

Ian H Frazer

Affiliations

Soon will be listed here.

Abstract

We recently demonstrated that Saccharomyces cerevisiae protoplasts can take up bovine papillomavirus type 1 (BPV1) virions and that viral episomal DNA is replicated after uptake. Here we demonstrate that BPV virus-like particles are assembled in infected S. cerevisiae cultures from newly synthesized capsid proteins and also package newly synthesized DNA, including full-length and truncated viral DNA and S. cerevisiae-derived DNA. Virus particles prepared in S. cerevisiae are able to convey packaged DNA to Cos1 cells and to transform C127 cells. Infectivity was blocked by antisera to BPV1 L1 but not antisera to BPV1 E4. We conclude that S. cerevisiae is permissive for the replication of BPV1 virus.

Citing Articles

Characterization of Episomal Replication of Bovine Papillomavirus Type 1 DNA in Long-Term Virion-Infected Saccharomyces Cerevisiae Culture.

Tu Q, Feng W, Chen Z, Li Q, Zhao Y, Chen J Virol Sin. 2021; 36(6):1492-1502.

PMID: 34460066 PMC: 8692549. DOI: 10.1007/s12250-021-00439-y.

Molecular design for recombinant adeno-associated virus (rAAV) vector production.

Aponte-Ubillus J, Barajas D, Peltier J, Bardliving C, Shamlou P, Gold D Appl Microbiol Biotechnol. 2017; 102(3):1045-1054.

PMID: 29204900 PMC: 5778157. DOI: 10.1007/s00253-017-8670-1.

Yeast and the AIDS virus: the odd couple.

Andreola M, Litvak S J Biomed Biotechnol. 2012; 2012:549020.

PMID: 22778552 PMC: 3385842. DOI: 10.1155/2012/549020.

An inhibitory interaction between viral and cellular proteins underlies the resistance of tomato to nonadapted tobamoviruses.

Ishibashi K, Naito S, Meshi T, Ishikawa M Proc Natl Acad Sci U S A. 2009; 106(21):8778-83.

PMID: 19423673 PMC: 2678887. DOI: 10.1073/pnas.0809105106.

Varying efficiency of long-term replication of papillomaviruses in Saccharomyces cerevisiae.

Rogers A, Loggen M, Lee K, Angeletti P Virology. 2008; 381(1):6-10.

PMID: 18829061 PMC: 2605936. DOI: 10.1016/j.virol.2008.08.038.

References

Cook J, Joyce J, George H, Schultz L, Hurni W, Jansen K . Purification of virus-like particles of recombinant human papillomavirus type 11 major capsid protein L1 from Saccharomyces cerevisiae. Protein Expr Purif. 1999; 17(3):477-84. DOI: 10.1006/prep.1999.1155. View

Zhao K, Frazer I, Jun Liu W, Williams M, Zhou J . Nucleotides 1506-1625 of bovine papillomavirus type 1 genome can enhance DNA packaging by L1/L2 capsids. Virology. 1999; 259(1):211-8. DOI: 10.1006/viro.1999.9714. View

Hostetter M . Integrin-like proteins in Candida spp. and other microorganisms. Fungal Genet Biol. 2000; 28(3):135-45. DOI: 10.1006/fgbi.1999.1165. View

Rossi J, Gissmann L, Jansen K, Muller M . Assembly of human papillomavirus type 16 pseudovirions in Saccharomyces cerevisiae. Hum Gene Ther. 2000; 11(8):1165-76. DOI: 10.1089/10430340050015211. View

Zhao K, Hengst K, Liu W, Liu Y, Liu X, McMillan N . BPV1 E2 protein enhances packaging of full-length plasmid DNA in BPV1 pseudovirions. Virology. 2000; 272(2):382-93. DOI: 10.1006/viro.2000.0348. View

Osen W, JOCHMUS I, Muller M, Gissmann L . Immunization against human papillomavirus infection and associated neoplasia. J Clin Virol. 2000; 19(1-2):75-8. DOI: 10.1016/s1386-6532(00)00090-1. View

Yeager M, Brown D, Martin M, Shah M, Cook J, Christensen N . Neutralization of human papillomavirus (HPV) pseudovirions: a novel and efficient approach to detect and characterize HPV neutralizing antibodies. Virology. 2000; 278(2):570-7. DOI: 10.1006/viro.2000.0674. View

Liu W, Qi Y, Zhao K, Liu Y, Liu X, Frazer I . Association of bovine papillomavirus type 1 with microtubules. Virology. 2001; 282(2):237-44. DOI: 10.1006/viro.2000.0728. View

Klotz S, Pendrak M, Hein R . Antibodies to alpha5beta1 and alpha(v)beta3 integrins react with Candida albicans alcohol dehydrogenase. Microbiology (Reading). 2001; 147(Pt 11):3159-64. DOI: 10.1099/00221287-147-11-3159. View

10.

Liu Y, You H, Chiriva-Internati M, Korourian S, Lowery C, Carey M . Display of complete life cycle of human papillomavirus type 16 in cultured placental trophoblasts. Virology. 2002; 290(1):99-105. DOI: 10.1006/viro.2001.1135. View

11.

Angeletti P, Kim K, Fernandes F, Lambert P . Stable replication of papillomavirus genomes in Saccharomyces cerevisiae. J Virol. 2002; 76(7):3350-8. PMC: 136042. DOI: 10.1128/jvi.76.7.3350-3358.2002. View

12.

Zhao K, Frazer I . Replication of bovine papillomavirus type 1 (BPV-1) DNA in Saccharomyces cerevisiae following infection with BPV-1 virions. J Virol. 2002; 76(7):3359-64. PMC: 136048. DOI: 10.1128/jvi.76.7.3359-3364.2002. View

13.

Meyers C, Bromberg-White J, Zhang J, Kaupas M, Bryan J, Lowe R . Infectious virions produced from a human papillomavirus type 18/16 genomic DNA chimera. J Virol. 2002; 76(10):4723-33. PMC: 136126. DOI: 10.1128/jvi.76.10.4723-4733.2002. View

14.

Hirt B . Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol. 1967; 26(2):365-9. DOI: 10.1016/0022-2836(67)90307-5. View

15.

Laemmli U . Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970; 227(5259):680-5. DOI: 10.1038/227680a0. View

16.

Valenzuela P, Medina A, Rutter W, Ammerer G, Hall B . Synthesis and assembly of hepatitis B virus surface antigen particles in yeast. Nature. 1982; 298(5872):347-50. DOI: 10.1038/298347a0. View

17.

Heidenreich F, Dierich M . Candida albicans and Candida stellatoidea, in contrast to other Candida species, bind iC3b and C3d but not C3b. Infect Immun. 1985; 50(2):598-600. PMC: 262001. DOI: 10.1128/iai.50.2.598-600.1985. View

18.

Edwards Jr J, Gaither T, Oshea J, Rotrosen D, Lawley T, Wright S . Expression of specific binding sites on Candida with functional and antigenic characteristics of human complement receptors. J Immunol. 1986; 137(11):3577-83. View

19.

KREIDER J, Howett M, Zaino R, Weber J . Laboratory production in vivo of infectious human papillomavirus type 11. J Virol. 1987; 61(2):590-3. PMC: 253985. DOI: 10.1128/JVI.61.2.590-593.1987. View

20.

Weinshenker B, Wilton S, Rice G . Phorbol ester-induced differentiation permits productive human cytomegalovirus infection in a monocytic cell line. J Immunol. 1988; 140(5):1625-31. View