Contribution of Candida Albicans ALS1 to the Pathogenesis of Experimental Oropharyngeal Candidiasis

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 2002 Aug 17

PMID 12183577

Citations 38

Authors

Yasuki Kamai

Mikie Kubota

Yoko Kamai

Tsunemichi Hosokawa

Takashi Fukuoka

Scott G Filler

Affiliations

Soon will be listed here.

Abstract

We investigated the contribution of Candida albicans ALS1, which encodes a candidal adhesin, to the pathogenesis of experimental murine oropharyngeal candidiasis. Our results indicate that the ALS1 gene product is important for the adherence of the organism to the oral mucosa during the early stage of the infection.

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