Convergent Extension: the Molecular Control of Polarized Cell Movement During Embryonic Development

Overview

Journal Dev Cell

Publisher Cell Press

Specialties Cell Biology
Reproductive Medicine

Date 2002 Jun 14

PMID 12062082

Citations 217

Authors

John B Wallingford

Scott E Fraser

Richard M Harland

Affiliations

Soon will be listed here.

Abstract

During development, vertebrate embryos undergo dramatic changes in shape. The lengthening and narrowing of a field of cells, termed convergent extension, contributes to a variety of morphogenetic processes. Focusing on frogs and fish, we review the different cellular mechanisms and the well-conserved signaling pathways that underlie this process.

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