K(2)CO(3)-catalyzed Michael Addition-lactonization Reaction of 1,2-allenyl Ketones with Electron-withdrawing Group Substituted Acetates. An Efficient Synthesis of Alpha-pyrone Derivatives

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2002 Feb 15

PMID 11843577

Citations 4

Authors

Shengming Ma

Shaohu Yin

Lintao Li

Fenggang Tao

Affiliations

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Abstract

[reaction: see text] Alpha-pyrone derivatives were synthesized via the base catalyzed or promoted reaction of 1,2-allenyl ketones and electron-withdrawing group substituted acetates. The reaction was believed to proceed through a Michael addition C-C double-bond migration-lactonization process.

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